Lesego studied law at the University of Botswana, and is currently a candidate for a Masters in Human Rights with the Centre for Human Rights, at the University of Pretoria. She has worked as an attorney in private practice, as well as a lawyer in national women’s rights organisations, and an international organisation. As a consultant, Lesego has developed curriculum, and conducted various other research work on an array of human rights concerns including gender-based violence litigation in Botswana, human rights violations against tribal minorities and indigenous persons with thematic focus on women’s rights, amongst others.  Lesego played a role in the implementation of the incremental approach towards strategic litigation in Botswana, leading up to the case on the decriminalisation of same-sex sexual intercourse in Botswana. Specifically, Lesego worked with the local movement in Botswana, as the lawyer in the case for the registration of the LGB organisation LEGABIBO (2014 and 2016). She was also the lawyer in the transgender rights cases in Botswana, which were decided favourably by the High Court in the country.

Lesego has also worked extensively with women’s rights organisations, in Botswana, on various legal aid programmes on women’s access to justice, primarily focusing on cases of violence against women, as well as women’s inheritance rights and women’s right to land ownership and control. At ISLA, Lesego is the Women’s Socio-Economic Rights (WSER) Lawyer. Her work has a regional focus, with a view at using the law as a tool for social change in various areas that affect economic justice.